A simple new competition assay for heparin binding in serum applied to multivalent PAMAM dendrimers.
نویسندگان
چکیده
We report a competition assay using our recently reported dye Mallard Blue, which allows us to identify synthetic heparin binders in competitive media, including human serum - using this we gain insight into the ability of PAMAM dendrimers to bind heparin, with the interesting result that low-generation G2-PAMAM is the preferred heparin binder.
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ورودعنوان ژورنال:
- Chemical communications
دوره 49 42 شماره
صفحات -
تاریخ انتشار 2013